"We firmly reject the recent unilateral coercive measures adopted" by the US government, Cuban Foreign Minister Bruno Rodriguez said on X.
These actions demonstrate an intention to impose collective punishment on the Cuban people, Rodriguez said, Xinhua reported.
He noted that the announcement coincided with May 1, when millions of Cubans take to the streets to denounce the US blockade and the energy siege.
"These measures are extraterritorial in nature and violate the United Nations Charter," Rodriguez said, adding that the United States has no right to impose measures against Cuba or against third countries or parties.
The comment came after US President Donald Trump on Friday signed an executive order imposing new sanctions on Cuba.