Kharrazi was targeted in a deliberate attack during the US-Israeli military aggression on Iran.
On April 1, during bombings in Tehran, Kharrazi's residence was struck by American-Israeli aircraft, which resulted in the martyrdom of his wife.
The US and the Israeli regime launched a large-scale unprovoked military campaign against Iran following the assassination of then Leader of the Islamic Revolution Ayatollah Seyed Ali Khamenei, along with several senior military commanders and civilians on February 28.
In retaliation, Iranian Armed Forces launched attacks on American and Israeli positions in the region, demonstrating their capability to strike back effectively. Despite initial expectations by the attackers of a swift victory, the Iranian response proved significantly more potent, inflicting heavy damage on US and Israeli military resources while rallying the nation's unity and resistance.
While the US president had issued an ultimatum, Pakistani mediation facilitated an agreement for a two-week ceasefire during which negotiations would take place in Islamabad. Iran has proposed a ten-point plan as the foundation for discussions, seeking terms such as the withdrawal of US forces from the region, lifting sanctions, and establishing control over the Strait of Hormuz.
The Supreme National Security Council of Iran emphasized on April 8 that the aggression led to a historic victory for Iran, compelling the US to accept negotiation terms, including a plan for guaranteed non-aggression and the cessation of hostilities.
Iran has stressed that the negotiations would not signify an end to the conflict but rather an extension of the battlefield into diplomatic efforts, with a clear stance of distrust towards the US.